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IL-22 R alpha 1

概要

Name:Interleukin-22 receptor
Target Synonym:
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:5
Lastest Research Phase:Phase 2 Clinical

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製造番号 種類 製品説明 構造 純度 特徴
IL1-H5258 Human Human IL-22 R alpha 1 Protein, Fc Tag
IL1-H5258-structure
IL1-H5258-sds
ACRO Quality

生物活性データの一部

IL1-H5258-BLI
 IL-22 R alpha 1 BLI

Loaded Human IL-22 R alpha 1 Protein, Fc Tag (Cat. No. IL1-H5258) on Protein A Biosensor, can bind Human IL-24 Protein, His Tag (Cat. No. IL4-H52H4) with an affinity constant of 1.71 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

IL1-H5258-ELISA
 IL-22 R alpha 1 ELISA

Immobilized Human IL-22, His Tag (Cat. No. IL2-H524a) at 5 μg/mL (100 μL/well) can bind Human IL-22 R alpha 1, Fc Tag (Cat. No. IL1-H5258) with a linear range of 2-78 ng/mL (QC tested).

Synonym Name

Interleukin-22 receptor subunit alpha-1,IL-22 receptor subunit alpha-1,IL-22R-alpha-1,IL-22RA1,Cytokine receptor class-II member 9,Cytokine receptor family 2 member 9,CRF2-9,ZcytoR11,IL22RA1,IL22R

Background

Clinical and Translational Updates

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Efmarodocokin alfa RO-7021610; UTTR-1147A; RG-7880 Phase 2 Clinical Genentech Inc Diabetic Foot; Coronavirus Disease 2019 (COVID-19); Graft vs Host Disease; Colitis, Ulcerative; Crohn Disease Details
Temtokibart ARGX-112; LEO-138559; LP-0145 Phase 2 Clinical Argenx Se, Leo Pharma Inc Dermatitis, Atopic Details
Eflepedocokin alfa F-652 Phase 2 Clinical Evive Biotech Ltd Hepatitis, Alcoholic; Pancreatitis; Coronavirus Disease 2019 (COVID-19); Graft vs Host Disease; Acute-On-Chronic Liver Failure Details
CK-0045 CK-0045 Phase 1 Clinical Cytoki Pharma ApS Details
ABBV-022 ABBV-022 Phase 1 Clinical Abbvie Inc Colitis, Ulcerative Details

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